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Genetic and Congenital Disorder

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A 23-year-old woman with history of sickle cell disease wants to have a child but worries that the child will be born with the disease.

a. What is the mother’s genotype in terms of sickle cell gene? Is she heterozygous or homozygous?

b. If the husband is found not to have the sickle cell gene, what is the probability of their child having the disease or being a carrier of the sickle cell trait?

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